Which is an example of nociceptive pain seen in late OA?

Which is an example of nociceptive pain seen in late OA?

• A. Pain at rest
• B. Ongoing or chronic pain
• C. Pain on movement
• D. Referred/multifocal/widespread pain

Answer: (D)

Nociceptive pain from late OA comes from activation of peripheral pain receptors in the joint structures when they are stimulated by use. It tends to be localized to the affected joint and worsens with movement or weight-bearing, reflecting mechanical irritation of cartilage, synovium, bone, or ligaments. Therefore, pain that is brought on by movement is the classic nociceptive pattern in late OA. Pain at rest may reflect inflammatory activity or other pain mechanisms, ongoing or chronic pain describes duration rather than mechanism, and referred or widespread pain points to mechanisms beyond a single joint, such as central sensitization or nociplastic processes.

Nociceptive pain from late OA comes from activation of peripheral pain receptors in the joint structures when they are stimulated by use. It tends to be localized to the affected joint and worsens with movement or weight-bearing, reflecting mechanical irritation of cartilage, synovium, bone, or ligaments.

Therefore, pain that is brought on by movement is the classic nociceptive pattern in late OA. Pain at rest may reflect inflammatory activity or other pain mechanisms, ongoing or chronic pain describes duration rather than mechanism, and referred or widespread pain points to mechanisms beyond a single joint, such as central sensitization or nociplastic processes.